Dear Chairman Grassley and Ranking Member Wyden,
The undersigned are writing to express our strong support for the reauthorization of the Patient Centered Outcomes Research Institute (PCORI). Our health care system requires solutions that are both
evidence-based and patient-centered, to improve care while also addressing health care spending.
PCORI is uniquely set up to meet this challenge, as it is the only organization dedicated to funding
comparative clinical effectiveness research (CER) studies comparing which treatment approaches work
best, for which patients, given their needs and preferences. The goal is to help health care providers and
payers better understand health care treatment options and to help patients and those who care for
them make better informed health and health care decisions. Delivering care that is most clinically
effective and incorporates outcomes that matter to patients is both cost effective and essential to our
well-being as a nation.
As of December 2018, PCORI has awarded more than $2.4 billion in grants to more than 600 research related projects in 44 states across the U.S. In 2014, PCORI saw the first large number of research results
from its funded studies reported in major medical journals. Several of these projects generated
particularly promising evidence for improving care and patient outcomes in key areas, such as
cardiovascular disease, prostate cancer, opioid prescribing, and type 2 diabetes management
…
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